|
KMID : 1134820230520050492
|
|
Journal of the Korean Society of Food Science and Nutrition
2023 Volume.52 No. 5 p.492 ~ p.498
|
|
|
UPLC-MS Assessment of THC and CBD Levels of Hemp Seeds, Hemp Seed Oil, and Hemp-Based Processed Foods Distributed in South Korea
|
|
Hwang Hee-Young
Kim Mee-Jeong
Shim Hye-Mi
Jeong Woo-Sik
|
|
|
Abstract
|
|
|
|
This study aims to verify the accuracy of the UPLC-MS method for analyzing Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) levels. The contents were investigated in hemp seeds, hemp seed oil, and processed foods containing hemp seeds in South Korea. Our results confirmed that the method was appropriate with high selectivity, reproducibility, linearity, and recovery for both THC (94.1∼108.3%) and CBD (84.9∼109.0%). It was determined that 13 out of the 16 tested products were within the suitable range of THC and CBD levels. However, three out of nine hemp seed oil products exceeded the standards for these compounds, indicating the need for continuous monitoring. The results of our study verify and conclude the reliability of LC-MS/MS as a method for determining THC and CBD concentrations in hemp seeds and hemp seed oil.
|
|
|
KEYWORD
|
|
|
THC, CBD, UPLC-MS, hemp seed oil, method validation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|